Before the fall, Adam and Eve lived harmoniously together as husband and wife. They lived in a beautiful garden God had created for their pleasure. They lived in luxury. Sin did not dominate the world. They had a perfect relationship with God and with each other.
After the fall, Adam and Eve fall into sin and misery. They became aware of their nakedness, and set out to cover themselves (Gen. 3:7). They hid themselves from God (Gen. 3:8). They also isolated themselves from God (Gen. 3:10). They had become fearful of God. Their relationship with each other weakened. Accusations were made, blame shifted, neither wanted to be held accountable, and they refused to admit they were wrong. Sin separated them from God and each other. Their relationship with each other and God was damaged.